Rescuers work at the site of a hotel building hit by a Russian missile strike, amid Russia's attack on Ukraine, in Kryvyi Rih, Dnipropetrovsk region, Ukraine, in this handout picture released March 6, 2025. Photo: State Emergency Service Of Ukrai/via Reuters

President Donald Trump's decision to pause all U.S. military aid and intelligence sharing has raised concerns that Ukraine's air defenses will become less effective in the days, weeks and months to come.

Ukraine's air force reported 112 drones and two missiles launched into the country overnight, with 68 drones shot down and 43 lost in flight.

The air force reported damage in the Kharkiv, Sumy, Odesa and Dnipropetrovsk regions.

In Dnipropetrovsk, a ballistic missile hit a hotel in the city of Kryvyi Rih -- Zelenskyy's hometown.

"A ballistic missile struck an ordinary hotel," the president wrote on social media. Four people were killed with more than 30 others injured, he added. The attack came shortly after a group of foreign humanitarian volunteers checked into the hotel, Zelenskyy said. None were hurt.

Sources told ABC News that two U.S. citizens were among the volunteers who survived the strike, working for the Charity fund Freedom Trust and Ukraine Relief organization.

"There must be no pause in the pressure on Russia to stop this war and terror against life," Zelenskyy wrote.

Russian missiles and drone attacks are a nightly occurrence in Ukraine. The country has become largely reliant on Western anti-air weapons to defeat incoming projectiles.

U.S. intelligence sharing with Ukraine had allowed Kyiv to give warnings to targeted areas ahead of Russian drone and missile strikes, tracking Russian aircraft taking off, drones being launched and missiles being fired.

A Ukrainian intelligence official told ABC News on Wednesday that the intelligence sharing pause included a halt in sharing U.S. satellite imagery through the Defense Intelligence Agency.

Zelenskyy is expected to travel to Brussels, Belgium, to meet with European leaders on Thursday, as he seeks further Western military and political support. The president has consistently requested more air defenses, an issue now more pressing amid the U.S. aid freeze.